John Wayne Casserole – A Cheesy, Southwestern Classic

John Wayne Casserole is a hearty, flavor-packed dish with Southwestern flair. Layered with seasoned ground beef, onions, peppers, tangy tomatoes, and a creamy cheesy topping over a tender biscuit base, this crowd-pleasing casserole is bold, comforting, and cowboy-approved!

🍴 Recipe Overview

• Prep Time: 15 minutes
• Cook Time: 35–40 minutes
• Total Time: 50–55 minutes
• Yield: 6–8 servings

🧂 Ingredients

• 1 lb ground beef
• 1 packet taco seasoning
• 1 cup chopped onions
• 1 cup chopped bell peppers (red & green)
• 1 can (10 oz) diced tomatoes with green chiles, drained
• 2 cups shredded cheddar cheese
• 1 cup shredded Monterey Jack cheese
• 1 cup mayonnaise or sour cream
• 2 cups biscuit mix (like Bisquick)
• 1 cup water

🔥 Instructions